The study of chemistry of natural products has had an overwhelming impact on the development of organic chemistry. The contributions of such giants as Robinson, Woodward and Barton in this field played a key role in its growing importance. About 40% of all medicines today are either directly or indirectly derived from natural sources, and nature continues to provide exciting new pharmacophores for research on drug design and development. Advances in chromatographic techniques and spectroscopy have facilitated the isolation and structure elucidation of complex primary and secondary metabolites from the plant and animal kingdom. The unraveling of this complexity has not only reinforced a deeper understanding of the fundamental chemistry that directs and manages these living processes, but it has also offered complex synthetic targets to organic chemists. The study of the chemistry of natural products has consequently had an overwhelming impact on the development of organic chemistry. The 1960's witnessed a shift in the emphasis to asymmetric synthesis, with respect to the establishment of new synthetic approaches to acquire the desired products in high enantiomeric excess. Microbial transformations have found a considerable number of applications in synthetic transformations, and the corticosteroid industry today relies on such transformations for industrial production. Other noteworthy examples are the application of catalytic antibodies in organic synthesis, and the applications of fermentation chemistry and plant tissue culture techniques for the preparation of important natural products.
The Natural Products Journal (NPJ) aims to publish original research articles, reviews and letters on all the latest and outstanding developments in natural products including isolation, purification, structure elucidation, synthesis, biosynthesis, biotransformations and bioactivity of terrestrial and marine compounds.
We are confident that The Natural Products Journal will soon achieve a very respectable status in its field and offer a preferred platform for the publication of important cutting edge research.