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Current Cancer Drug Targets

Volume 7 Issue 1
ISSN: 1568-0096
eISSN: 1873-5576

 

   All Titles

  Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response
  pp.79-89 (11) Authors: Shreya Kanodia, Laura M. Fahey, W. Martin Kast
 
 
      Abstract

The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for the decades required to develop HPV-related cancers, the virus must escape host immunity. HPV is a simple DNA virus that has evolved to escape immune attack by a combination of stealth and interference. This review focuses on the mechanisms by which HPV can evade recognition by the host immune system.

 
  Keywords: Papilloma virus, tumor immunology, immunotherapy, cancer
  Affiliation: Norris Comprehensive Cancer Center, ZNI 245, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA.
 
  Key: New Content Free Content Open Access Plus Subscribed Content

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