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Current Drug Delivery

Volume 8 Issue 3
ISSN: 1567-2018
eISSN: 1875-5704

 

   All Titles

  Peptide-Based Subunit Nanovaccines
  pp.282-289 (8) Authors: Mariusz Skwarczynski, Istvan Toth
 
 
      Abstract

Classical vaccines incorporating live or attenuated microorganisms possess several disadvantages and cannot be applied against cancer and some pathogens. Modern vaccines utilizing immunogenic subunits derived from a particular pathogen are able to overcome these obstacles but need a specific delivery system for their efficacy. Nanotechnology has opened a new window into these delivery methodologies. A nano-sized formulation of subunit vaccines has been proven to be very effective in inducing cellular and humoral immune responses. Here, we review a number of peptide vaccine delivery strategies based on nanoparticles composed of polymers, peptides, lipids, and inorganic materials.

 
  Keywords: Subunit vaccine, peptide epitope, nanotechnology, nanoparticles, infectious diseases, Nanovaccine, autoimmunity, lipid carriers, inorganic materials, pathogens
  Affiliation: The University of Queensland, School of Chemistry and Molecular Biosciences, St Lucia, Qld 4072, Australia.
 
  Key: New Content Free Content Open Access Plus Subscribed Content

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