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Current Drug Delivery

Volume 8 Issue 3
ISSN: 1567-2018
eISSN: 1875-5704


   All Titles

  Peptide-Based Subunit Nanovaccines
  pp.282-289 (8) Authors: Mariusz Skwarczynski, Istvan Toth

Classical vaccines incorporating live or attenuated microorganisms possess several disadvantages and cannot be applied against cancer and some pathogens. Modern vaccines utilizing immunogenic subunits derived from a particular pathogen are able to overcome these obstacles but need a specific delivery system for their efficacy. Nanotechnology has opened a new window into these delivery methodologies. A nano-sized formulation of subunit vaccines has been proven to be very effective in inducing cellular and humoral immune responses. Here, we review a number of peptide vaccine delivery strategies based on nanoparticles composed of polymers, peptides, lipids, and inorganic materials.

  Keywords: Subunit vaccine, peptide epitope, nanotechnology, nanoparticles, infectious diseases, Nanovaccine, autoimmunity, lipid carriers, inorganic materials, pathogens
  Affiliation: The University of Queensland, School of Chemistry and Molecular Biosciences, St Lucia, Qld 4072, Australia.
  Key: New Content Free Content Open Access Plus Subscribed Content

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