During the course of our investigation of longevity promoting natural products and Chinese herbs in the last 15 years, we come to the conclusion that in order to have healthy, productive and graceful maturing, it is necessary to maintain a dynamic balance between proinflammatory and anti-inflammatory loads. This may also help to prevent cancer as well as premature degeneration of various organ systems. Modern life style and food intake tend to overload proinflammatory factors. To overcome this it is desirable to regularly consume fresh fruits, vegetables and multiple grains, various beans including soybeans and/or minimally processed, unbleached products. When this is not sufficient or possible, taking proper dietary supplements under the guidance of knowledgeable health professional can be helpful.