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Current Molecular Medicine

Volume 5 Issue 7
ISSN: 1566-5240
eISSN: 1875-5666

 

   All Titles

  Craniofacial Anomalies: From Development to Molecular Pathogenesis
  pp.699-722 (24) Author: David P.C. Rice
 
 
      Abstract

Advances in developmental biology combined with progress in human genetics are helping us decipher how the craniofacial region develops and how the consequences of misdirected development result in malformation. This review describes the molecular etiology of a number of craniofacial developmental anomalies. The more common craniofacial anomalies cleft lip and palate and craniosynostosis, as well as cleidocranial dysplasia, hemifacial microsomia, holoprosencephaly, enlarged parietal foramina, Treacher Collins syndrome and cherubism are discussed.

 
  Keywords: Cleft lip and palate, craniosynostosis, holoprosencephaly, hemifacial microsomia, Treacher Collins syndrome, cleidocranial dysplasia, parietal foramina, cherubism, craniofacial development
  Affiliation: Departments ofCraniofacial Development and Orthodontics, King's College London,London, UK.
 
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