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Current Physical Chemistry

Volume 1 Issue 4
ISSN: 1877-9468
eISSN: 1877-9476

 

   All Titles

  DNA Biosensing Using Field Effect Transistors
  pp.276-291 (16) Authors: Tatsuro Goda, Yuji Miyahara
doi: 10.2174/10276
 
 
      Abstract

This article focuses on recent advances and developments of field effect transistor (FET) devices for detecting DNA recognition events such as hybridization, SNP genotyping and primer extension. The unique features of FET biosensors highlight the potential advantages for high-throughput detection of DNA molecules in a label-free manner. In particular, FET devices represent a potential platform for the development of the next-generation DNA sequence instruments based on semiconductor technology. We also review an emerging class of FET devices that use nanomaterials such as silicon nanowires and single-walled carbon nanotubes as a gate channel for the ultrasensitive detection of biological analytes.

 
  Keywords: Biosensor, carbon nanotube, DNA sequencer, field effect transistor, Hybridization, Nanowire, SNP, DNA sequencing, ISFET, nanomaterials
  Affiliation: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University 2-3-10 Kanda- Surugadai, Chiyoda, Tokyo 101-0062, Japan.
 
  Key: New Content Free Content Open Access Plus Subscribed Content

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