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Letters in Organic Chemistry

Volume 2 Issue 7
ISSN: 1570-1786

 

   All Titles

  A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones
  pp.637-639 (3) Authors: V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna, A. Mehta
 
 
      Abstract

A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.

 
  Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation
  Affiliation: Department of MedicinalChemistry, Ranbaxy Research Laboratories, Plot no 20, Sector18, Udyog Vihar, Gurgaon -122001, Haryana, India.
 
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