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A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones
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pp.637-639 (3) Authors: V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna, A. Mehta |
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| Abstract |
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A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps. |
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Keywords:
chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation |
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Affiliation:
Department of MedicinalChemistry, Ranbaxy Research Laboratories, Plot no 20, Sector18, Udyog Vihar, Gurgaon -122001, Haryana, India. |
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