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Sulphamic Acid (H2NSO3H) Catalysed One Pot Synthesis of 3,4-Dihydropyrimidin-2(1h)-Ones and their Thione Analogues
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pp.662-664 (3) Authors: S. A. Kotharkar, M. R. Jadhav, R. R. Nagawade, S. S. Bahekar, D. B. Shinde |
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| Abstract |
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The substituted 3,4-dihydropyrimidin-2(1H)-ones and their thione analogues have been prepared Via Biginelli condensation using aldehyde, 1,3-dicarbonyl compound and urea or thiourea under the catalyst of sulphamic acid (H2NSO3H). The method is simple, cost-effective, and gives good yields in a shorter reaction time. |
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Keywords:
sulphamic acid, catalyst, biginelli reaction |
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Affiliation:
Department of ChemicalTechnology, Dr Babasaheb Ambedkar Marathwada University,Aurangabad - 431004 (M.S.), India. |
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