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Mini-Reviews in Medicinal Chemistry

Volume 9 Issue 2
ISSN: 1389-5575
eISSN: 1875-5607

 

   All Titles

  Natural Product Inhibitors of Hsp90: Potential Leads for Drug Discovery
  pp.140-152 (13) Authors: M. W. Amolins, B. S.J. Blagg
 
 
      Abstract

Heat shock protein 90 has emerged as a promising target for the treatment of cancer and neurodegenerative diseases. This review summarizes recent advancements towards the development of natural products as they pertain to the biological and chemical understanding of this molecular chaperone.

 
  Keywords: Hsp90, inhibitors, cancer, neurodegenerative diseases, natural products
  Affiliation: Department of Medicinal Chemistry, The University of Kansas, 1251 Wescoe Hall Drive, Malott 4070, Lawrence, Kansas 66045-7563, USA.
 
  Key: New Content Free Content Open Access Plus Subscribed Content

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